Københavns Universitet

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PhD fellow in Epigenetics at Københavns Universitet

Department of Plant and Environmental Sciences, Faculty of Science at University of Copenhagen is offering a PhD scholarship in Epigenetics commencing 1 January 2021 or as soon as possible thereafter.
Description of the scientific environment
The Department of Plant and Environmental Sciences constitutes a stimulating and international research environment. The current position is financially supported by a Danish National Research Foundation Grant to Associate Professor Sebastian Marquardt. The position will be located at Copenhagen Plant Science Centre (CPSC) with state-of-the-art research facilities. The aim of CPSC is to create a cross-disciplinary scientific environment that links plant scientists and advances research from bench to application.
Project description
We are looking for an exceptionally motivated PhD student to elucidate the effects of epigenetic signaling during long non-coding RNA (lncRNA) transcription on “genomic punctuation”. The project operates at the interface between the research areas of: epigenetics, RNA biology, RNA polymerase II (RNAPII) transcription and genomics. You will be based in the laboratory of Sebastian Marquardt, University of Copenhagen, Denmark, and visit the laboratory of Steve Jacobsen, University California Los Angeles, USA, to perform part of your project.
You will dissect the molecular mechanism of epigenetic signaling associated with RNAPII transcription elongation in Arabidopsis. A focus will be on histone 3 lysine 4 mono-methylation (H3K4me1) signaling. We are looking for a new team member enthusiastic about molecular genetic, biochemical and genomic approaches to characterize key players involved. We expect to uncover chromatin-based effects on RNAPII elongation, likely linked to gene regulation by overlapping lncRNA transcription. This Ph.D. project involves design, execution and analysis of transcriptomics and epigenomics Next-Generation Sequencing (NGS) data. Expertise and enthusiasm to analyze NGS data characterize candidates that match the profile for this position.
Principal supervisor isAssociate Professor Sebastian Marquardt,Copenhagen Plant Science Centre, e-mail: sebastian.marquardt@plen.ku.dk, Direct Phone: +4535331305.
Job description
The position is available for a 3-year period and your key tasks as a PhD student at SCIENCE are:
  • To manage and carry through your research project
  • Attend PhD courses
  • Write scientific articles and your PhD thesis
  • Teach and disseminate your research
  • To stay at an external research institution (UCLA, USA) for a few months
  • Work for the department

Formal requirements
Applicants should hold an MSc degree in Biology/Biochemistry/Molecular Biology or related fields with very good results and good English skills. As criteria for the assessment of your qualifications, emphasis will also be laid on previous publications (if any) and relevant work experience, particular in the area of NGS data analysis.
Terms of employment
The position is covered by the Memorandum on Job Structure for Academic Staff.
Terms of appointment and payment accord to the agreement between the Ministry of Finance and The Danish Confederation of Professional Associations on Academics in the State.
The starting salary is currently at a minimum DKK 331,125 (approx. €43,750) including annual supplement (+ pension at a minimum DKK 53,811). Negotiation for salary supplement is possible.
Application Procedure
The application, in English, must be submitted electronically by clicking APPLY NOW below.
  • Cover Letter, stating which PhD project you are applying for and detailing your motivation and background for applying for the specific PhD project.
  • CV
  • Diploma and transcripts of records (BSc and MSc)
  • List of publications (if any)
  • 1-3 reference letters (if any)

The University wishes our staff to reflect the diversity of society and thus welcomes applications from all qualified candidates regardless of personal background.
The deadline for applications is 15 August 2020, 23:59 GMT +2.
After the expiry of the deadline for applications, the authorized recruitment manager selects applicants for assessment on the advice of the Interview Committee. Afterwards an assessment committee will be appointed to evaluate the selected applications. The applicants will be notified of the composition of the committee and the final selection of a successful candidate will be made by the Head of Department, based on the recommendations of the assessment committee and the interview committee.
The main criterion for selection will be the research potential of the applicant and the above mentioned skills. The successful candidate will then be requested to formally apply for enrolment as a PhD student at the PhD school of Science. You can read more about the recruitment process athttps://employment.ku.dk/faculty/recruitment-process/.
For specific information about the PhD scholarship, please contact the principal supervisor, Associate Professor Sebastian Marquardt, Copenhagen Plant Science Centre, e-mail: sebastian.marquardt@plen.ku.dk , Direct Phone: +4535331305.
General information about PhD programmes at SCIENCE is available at https://www.science.ku.dk/phd.

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