A 2-year Post-Doctoral Fellowship in supramolecular and bioorganic chemistry under the supervision of Associate Professor Sophie Beeren is available at the Technical University of Denmark. The project is funded by the Carlsberg Foundation Young Research Fellowship grant entitled ‘Enzyme-mediated Dynamic Combinatorial Chemistry’. The successful candidate will join a young and ambitious, international research team, which is a part of the Organic and Inorganic Chemistry section at DTU Chemistry.
Research in the group is focused on supramolecular chemistry in water. We aim to understand how non-covalent interactions allow molecules interact, to recognise each other, to fold and assemble into larger, multi-component systems. We take inspiration from biological systems and exploit the tools of biochemistry to build new and complex chemical architectures, dynamic systems, host-gest complexes and adaptive materials.
The project will explore the use of enzyme-catalysed reactions in templated dynamic covalent synthesis – combining supramolecular chemistry with enzymology This methodology will be developed towards the synthesis of carbohydrate-based receptors and stimuli-responsive materials.
Responsibilities and tasks
The work will include the design, synthesis and characterisation of molecular building blocks and supramolecular assemblies, enzymatic synthesis, analysis of dynamic oligosaccharide mixtures, and physical studies using spectroscopy (NMR, UV-Vis, fluorescence and CD spectroscopy) to investigate conformation, binding phenomena and self-assembly. Active dissemination of the obtained results, in scientific articles and through participation in international conferences, is an integral part of the job. The candidate hired to the position will also be expected to take some responsibility for guiding and training students in the group, engage in some teaching, and perform a limited number of administrative tasks.
The successful candidate should have a PhD in Supramolecular or Organic Chemistry. Previous post-doctoral experience is an advantage. Extensive experience working with spectroscopy (NMR and optical), chromatography analysis (HPLC, LC-MS), and/or organic synthesis is essential. Knowledge within the field of biochemistry is an advantage but not essential. Most importantly, the candidate should be highly motivated, able to work both independently and collaboratively, and should be confident in both written and spoken English. The applicant should strive towards scientific excellence, be ambitious and hard-working. Only applicants who seek to be among the brightest in their field and conduct science at the highest international level will be considered.
DTU is a leading technical university globally recognized for the excellence of its research, education, innovation and scientific advice. We offer a rewarding and challenging job in an international environment. We strive for academic excellence in an environment characterized by collegial respect and academic freedom tempered by responsibility.
Applications must be submitted as one PDF file containing all materials to be given consideration. To apply, please open the link "Apply online", fill out the online application form, and attach all your materials in English in one PDF file.
The file must include
- Application (cover letter)
- Diploma (MSc/PhD)
- List of publications
- Contact details for at least two academic referees
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